| Name | Recombinant Mouse TACI/TNFRSF13B Fc Chimera Protein, CF |
|---|---|
| Supplier | R&D Systems |
| Catalog | 1041-TC |
| Category | Protein |
| Prices | $329.00 |
| Sizes | 50 µg |
| Species Reactivities | Mouse |
| Nature | Recombinant |
| Source | Mouse myeloma cell line, NS0-derived Mouse TACI (Phe5 - Thr129) Accession # Q9ET35 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus |
| Purity | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain |
| Bioactivity | Measured by its ability to inhibit BAFF-mediated proliferation of anti-IgM stimulated mouse B cells. Moore, P.A. et al . (1999) Science 285 :260; Gross, J.A. et al . (2000) Nature 404 :995; Schneider, P. et al . (1999) J. Exp. Med. 189 :1747. The ED 50 for this effect is 3‑10 ng/mL in the presence of 2.5 ng/mL of rhBAFF. |
| Endotoxin | <0.10 EU per 1 μg of the protein by the LAL method. |
| SwissProt/Accession | Q9ET35 |
| Gene | Tnfrsf13b |
| Sequence | Phe5 |
| Supplier Page | Shop |
Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kumpfel T, Crawford HC, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E. J Immunol. 2015 Jan 15;194(2):542-52.
Kotani Y, Kunisawa J, Suzuki Y, Sato I, Saito T, Toba M, Kohda N, Kiyono H. PLoS One. 2014 Mar 14;9(3):e91857.
Kimberley FC, van der Sloot AM, Guadagnoli M, Cameron K, Schneider P, Marquart JA, Versloot M, Serrano L, Medema JP. J Biol Chem. 2012 Oct 26;287(44):37434-46.
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace WW, Fagarasan S. Immunity. 2010 Jul 23;33(1):71-83.