Recombinant Mouse ACE-2 Protein, CF

• Supplier: R&D Systems
• Catalog: 3437-ZN
• Category: Protein
• Prices: $329.00
• Sizes: 10 µg
• Species Reactivities: Mouse
• Nature: Recombinant
• Source: Chinese Hamster Ovary cell line, CHO-derived Gln18-Thr740, with a C-terminal 10-His tag
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH (Catalog # ES007 ). The specific activity is >400 pmol/min/µg, as measured under the described conditions. See Activity Assay Protocol on www.RnDSystems.com
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: NP_081562
• Gene: Ace2
• Sequence: No results obtained: Gln18 predicted

Product References

ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing - ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing

Riquelme C, Acuna MJ, Torrejon J, Rebolledo D, Cabrera D, Santos RA, Brandan E. PLoS One. 2014 Apr 2;9(4):e93449.

ACE2 links amino acid malnutrition to microbial ecology and intestinal - ACE2 links amino acid malnutrition to microbial ecology and intestinal

Hashimoto T, Perlot T, Rehman A, Trichereau J, Ishiguro H, Paolino M, Sigl V, Hanada T, Hanada R, Lipinski S, Wild B, Camargo SM, Singer D, Richter A, Kuba K, Fukamizu A, Schreiber S, Clevers H, Verrey F, Rosenstiel P, Penninger JM. Nature. 2012 Jul 25;487(7408):477-81.

Major role for ACE-independent intrarenal ANG II formation in type II diabetes. - Major role for ACE-independent intrarenal ANG II formation in type II diabetes.

Park S, Bivona BJ, Kobori H, Seth DM, Chappell MC, Lazartigues E, Harrison-Bernard LM. Am J Physiol Renal Physiol. 2010 Jan;298(1):F37-48. doi: