Recombinant Human Thrombospondin-2 Protein, CF

• Supplier: R&D Systems
• Catalog: 1635-T2
• Category: Protein
• Prices: $329.00
• Sizes: 50 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Gly19-Ile1172, with a C-terminal 10-His tag
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by the ability of the immobilized protein to support the adhesion of SVEC4‑10 mouse vascular endothelial cells. Recombinant Human Thrombospondin‑2 (rhThrombospondin-2) is coated to 96 well plates at 10 µg/mL (100 µL/well) overnight then reduced with 20 mM DTT for 30 minutes. When 2 x 10 4 cells/well are added to rhThrombospondin-2 coated plates, >55% will adhere after one hour at 37 °C. Optimal dilutions should be determined by each laboratory for each application.
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: P35442
• Gene: THBS2
• Sequence: Gly19

Product References

Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of - Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of

Chen PC, Tang CH, Lin LW, Tsai CH, Chu CY, Lin TH, Huang YL. J Hematol Oncol. 2017 Jan 25;10(1):33.

Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. - Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome.

Hellbach N, Weise SC, Vezzali R, Wahane SD, Heidrich S, Roidl D, Pruszak J, Esser JS, Vogel T. Hum Mol Genet. 2014 Dec 1;23(23):6177-90.

Protective astrogenesis from the SVZ niche after injury is controlled by Notch - Protective astrogenesis from the SVZ niche after injury is controlled by Notch

Benner EJ, Luciano D, Jo R, Abdi K, Paez-Gonzalez P, Sheng H, Warner DS, Liu C, Eroglu C, Kuo CT. Nature. 2013 May 16;497(7449):369-73.