Recombinant Human Notch-3 (aa 40-467) Fc Chimera Protein, CF

• Supplier: R&D Systems
• Catalog: 1559-NT
• Category: Protein
• Prices: $329.00
• Sizes: 50 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Spodoptera frugiperda , Sf 21 (stably transfected)-derived Human Notch-3 (Ala40 - Glu467) Accession # Q9UM47 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its binding ability in a functional ELISA. Immobilized rhNotch-3/Fc Chimera can bind rrJagged-1/Fc Chimera with an apparent K D <10 nM.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: Q9UM47
• Gene: NOTCH3
• Sequence: Ala40

Product References

NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in - NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in

Kayamori K, Katsube K, Sakamoto K, Ohyama Y, Hirai H, Yukimori A, Ohata Y, Akashi T, Saitoh M, Harada K, Harada H, Yamaguchi A. PLoS One. 2016 Apr 28;11(4):e0154112.

Inhibition of Dll4-mediated signaling induces proliferation of immature vessels - Inhibition of Dll4-mediated signaling induces proliferation of immature vessels

Scehnet JS, Jiang W, Kumar SR, Krasnoperov V, Trindade A, Benedito R, Djokovic D, Borges C, Ley EJ, Duarte A, Gill PS. Blood. 2007 Jun 1;109(11):4753-60. Epub 2007 Feb 20.