| Name | Recombinant Human Integrin alpha L beta 2 Protein, CF |
|---|---|
| Supplier | R&D Systems |
| Catalog | 3868-AV |
| Category | Protein |
| Prices | $359.00 |
| Sizes | 50 µg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | Chinese Hamster Ovary cell line, CHO-derived Human Integrin alpha L (Tyr26-Met1089) Accession # P20701 acidic tail Human Integrin beta 2 (Gln23-Asn700) Accession # P05107 basic tail N-terminus C-terminus |
| Purity | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain |
| Bioactivity | Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with ICAM-1. When 5 x 10 4 cells/well are added to Integrin alpha L beta 2-coated plates (5 µg/mL, 100 µL/well), 60‑80% of the cells will adhere after 1 hour at 37° C in the presence of 1 mM MnCl 2 . |
| Endotoxin | <1.0 EU per 1 μg of the protein by the LAL method. |
| SwissProt/Accession | P20701 (Integrin alpha L) & P05107 (Integrin beta 2) |
| Gene | ITGAL |
| Sequence | Tyr26 (Integrin alpha L) & No results obtained: Gln23 predicted (Integrin beta 2) |
| Supplier Page | Shop |
Chakraborty S, Nunez D, Hu SY, Domingo MP, Pardo J, Karmenyan A, Chiou A. PLoS One. 2014 Jul 17;9(7):e102572.
Arthos J, Cicala C, Martinelli E, Macleod K, Van Ryk D, Wei D, Xiao Z, Veenstra TD, Conrad TP, Lempicki RA, McLaughlin S, Pascuccio M, Gopaul R, McNally J, Cruz CC, Censoplano N, Chung E, Reitano KN, Kottilil S, Goode DJ, Fauci AS. Nat Immunol. 2008 Mar;9(3):301-9.