| Name |
Recombinant Mouse B7.1 (CD80)-Fc Chimera (carrier-free)
|
| Supplier |
Biolegend
|
| Catalog |
555404
|
| Category |
Protein
|
| Prices |
$125.00, $295.00
|
| Sizes |
25 µg, 100 µg
|
| Species Reactivities |
Mouse
|
| Nature |
Recombinant
|
| Source |
Mouse B7.1, amino acids (Asp37-Lys245) (Accession# NP_033985.3), was expressed in CHO cells with a C-terminal His-Fc tag and a linker sequence.
|
| Purity |
>95%, as determined by Coomassie stained SDS-PAGE.
|
| Bioactivity |
Immobilized mouse B7.1 induces proliferation of human T cells in the presence of anti-human CD3. The ED 50 is 2.25 - 9.0 µg/mL. In addition, mouse B7.1 induces IL-2 production on activated T cells. Results may vary depending on human donors.
|
| Endotoxin |
Less than 1.0 EU per µg of protein as determine by the LAL method.
|
| SwissProt/Accession |
NP_033985.3),
|
| Gene |
Cd80
|
| Description |
The B7 family of proteins are structurally related, cell membrane-associated molecules that regulate immune responses by delivering costimulatory or coinhibitory signals via their ligands
|
| Supplier Page |
Shop
|
Recombinant mouse B7.1, when immobilized on a plate (100 µl/well), is able to induce proliferation of human T cells in the presence of anti-CD3 antibody in a dose dependent manner. The ED 50 is 2.25 - 9.0 µg/ml. Results may vary depending on human donors.