Active human ErbB 3 protein fragment

Name Active human ErbB 3 protein fragment
Supplier Abcam
Catalog ab155631
Category Protein
Prices $465.00
Sizes 200 µg
Applications FA SDS-PAGE
Species Reactivities Human
Nature Recombinant
Source HEK 293 cells
Purity >95% by SDS-PAGE .
Bioactivity Measured by its ability to inhibit the biological activity of Neuregulin1-ß1 on MCF-7 Human breast cancer cells. The ED 50 for this effect is typically 1.5-6.0 µg/ml in the presence of 10 ng/ml Recombinant Human NRG1-ß1/HRG1-ß1 Extracellular Domain.
Endotoxin < 1.000 Eu/µg
SwissProt/Accession P21860
Gene ERBB3
Residue 20 to 643
Sequence SEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTG HNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFV MLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRD RDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHCF GPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLT FQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKM CEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLN GDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIG GRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLN WTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLS CRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSG SDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQ GCKGPELQDCLGQTLVLIGKTHLT
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