Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
ATP6V0C / VATL is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17.
Gene Name: | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c |
Family/Subfamily: | Transporter , ATPase - V type |
Synonyms: | ATP6V0C, ATPL, VATL, Vma3, VPPC, ATP6C, ATP6L |
Target Sequences: | NM_001694 NP_001685.1 P27449 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.