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p-Src Antibody (pY530.31): sc-136012
- p-Src Antibody (pY530.31) is a mouse monoclonal IgG2b provided at 50 µg/0.5 ml
- raised against a short amino acid sequence containing phosphorylated Tyr 528 of Fyn of human origin
- recommended for detection of Tyr 530 phosphorylated c-Src of human origin, Tyr 535 phosphorylated c-Src of mouse origin, and Tyr 528 phosphorylated Fyn of human and mouse origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-Src Antibody (pY530.31). This work is in progress.
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SEE ALSO...
The major translational products of the Src gene family are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences. By virtue of their common structural motifs, the Src family is composed of nine members in vertebrates, including c-Src, c-Yes, Fgr, Yrk, Fyn, Lyn, Hck, Lck and Blk. Src family kinases, which contain an amino-terminal cell membrane anchor followed by SH3 and SH2 domains, transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src family members are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular locations of Src family kinases may be important for the regulation of specific cellular processes, such as mitogenesis, cytoskeletal organization and membrane trafficking. c-Src (also designated pp60Src, Src p60 and proto-oncogene tyrosine protein kinase Src) is expressed in a broad range of tissue and cell types, although the highest levels of c-Src are detected in neuronal tissues and platelets. c-Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Src Antibody (pY530.31) | sc-136012 | 50 µg/0.5 ml | $310.00 |