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PGM 1 Antibody (Y-173): sc-100411
- PGM 1 Antibody (Y-173) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 100 µg/ml
- raised against recombinant PGM 1 of human origin
- recommended for detection of PGM 1 of human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PGM 1 Antibody (Y-173). This work is in progress.
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Phosphoglucomutase, which belongs to the phophohexose mutase family, plays a role in glycogen catabolism (glycogenolysis) as well as in the process of glycogen synthesis (glycogenesis). During glycogenolysis, PGM converts glucose-1-phosphate to glucose-6-phosphate, thus promoting glycolysis and the pentose phosphate pathway. During glycogenesis, PGM functions in the opposite manner, converting glucose-6-phosphate into glucose-1-phosphate, to facilitate glycogen synthesis. PGM has three structural loci: PGM1, PGM2 and PGM3. These three genetic forms of PGM differ in amino acid sequences but catalyze the same reactions, therefore indicating that they are isozymes. PGM1, a 562 amino acid protein, is highly polymorphic; three mutations and four intragenic recombination events between the three mutation sites generate eight protein variants. All phosphoglucomutases act as monomers and bind one magnesium ion per subunit.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PGM 1 Antibody (Y-173) | sc-100411 | 100 µg/ml | $327.00 |