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PP1β Antibody (A-6): sc-365678
- PP1β Antibody (A-6) is a mouse monoclonal IgG2b κ PP1β antibody, cited in 10 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 295-322 at the C-terminus of PP1β of human origin
- PP1 beta Antibody (A-6) is recommended for detection of PP1β of mouse, rat, human and origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine, porcine and avian
- Anti-PP1 beta Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PP1β (A-6): sc-365678.
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PP1β Antibody (A-6) for WB applications. These reagents are now offered in bundles with PP1β Antibody (A-6) (see ordering information below).
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PP1β Antibody (A-6) is an IgG2b κ mouse monoclonal PP1 beta antibody (also designated PP1β antibody) that detects the PP1 beta protein of mouse, rat and human origin by WB, IP, IF and ELISA. PP1β Antibody (A-6) is available as both the non-conjugated anti-PP1 beta antibody form, as well as multiple conjugated forms of anti-PP1 beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP1 family is comprised of subfamily members PP1α, PP1β and PP1γ, which are MgATP-dependent enzymes. PP1 inactivity is maintained through its association with the inhibitory protein NIPP-1 (nuclear inhibitor of PP1). Phosphorylation of NIPP-1 by cAMP-PK or casein kinase II results in the release of active PP1.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PP1β Antibody (A-6) | sc-365678 | 200 µg/ml | $310.00 | |||
PP1β Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-529436 | 200 µg Ab; 10 µg BP | $348.00 | |||
PP1β Antibody (A-6): m-IgGκ BP-HRP Bundle | sc-522324 | 200 µg Ab, 40 µg BP | $348.00 | |||
PP1β Antibody (A-6): m-IgG2b BP-HRP Bundle | sc-550110 | 200 µg Ab; 10 µg BP | $348.00 | |||
PP1β Antibody (A-6) AC | sc-365678 AC | 500 µg/ml, 25% agarose | $408.00 | |||
PP1β Antibody (A-6) HRP | sc-365678 HRP | 200 µg/ml | $310.00 | |||
PP1β Antibody (A-6) FITC | sc-365678 FITC | 200 µg/ml | $324.00 | |||
PP1β Antibody (A-6) PE | sc-365678 PE | 200 µg/ml | $337.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 488 | sc-365678 AF488 | 200 µg/ml | $350.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 546 | sc-365678 AF546 | 200 µg/ml | $350.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 594 | sc-365678 AF594 | 200 µg/ml | $350.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 647 | sc-365678 AF647 | 200 µg/ml | $350.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 680 | sc-365678 AF680 | 200 µg/ml | $350.00 | |||
PP1β Antibody (A-6) Alexa Fluor® 790 | sc-365678 AF790 | 200 µg/ml | $350.00 | |||
PP1β (A-6) Neutralizing Peptide | sc-365678 P | 100 µg/0.5 ml | $67.00 |