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Amphiregulin Antibody (C-1): sc-393433
- Amphiregulin Antibody (C-1) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 161-185 near the C-terminus of Amphiregulin of human origin
- recommended for detection of precursor and mature Amphiregulin of mouse, rat and human origin by WB, IP, IF and ELISA
- See Amphiregulin (G-4): sc-74501 for Amphiregulin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Amphiregulin Antibody (C-1) for WB applications. These reagents are now offered in bundles with Amphiregulin Antibody (C-1) (see ordering information below).
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SEE ALSO...
Epidermal growth factor (EGF) family member Amphiregulin was initially characterized as a schwannoma-derived growth factor (SDGF) that was expressed in response to androgen in the SC2G murine cell line. Amphiregulin has subsequently been characterized as an important growth factor for normal human keratinocyte proliferation. Amphiregulin is produced and secreted by keratinocytes and acts as an autocrine growth factor. Amphiregulin binds ErbB-1, which is essential for epithelial development in the skin, lung and gastrointestinal tract. Withdrawl of Amphiregulin has been shown to result in down regulation of telomerase activity in human keratinocytes and this suggests that Amphiregulin plays a role in cell senescence.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Amphiregulin Antibody (C-1) | sc-393433 | 200 µg/ml | $310.00 | |||
Amphiregulin Antibody (C-1): m-IgG Fc BP-HRP Bundle | sc-538215 | 200 µg Ab; 10 µg BP | $348.00 | |||
Amphiregulin Antibody (C-1): m-IgGκ BP-HRP Bundle | sc-535783 | 200 µg Ab; 40 µg BP | $348.00 | |||
Amphiregulin Antibody (C-1): m-IgG2a BP-HRP Bundle | sc-548234 | 200 µg Ab; 10 µg BP | $348.00 | |||
Amphiregulin (C-1) Neutralizing Peptide | sc-393433 P | 100 µg/0.5 ml | $67.00 |