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pan 14-3-3 Antibody (B-11): sc-133232
- pan 14-3-3 Antibody (B-11) is a mouse monoclonal IgG1 κ, cited in 9 publications, provided at 200 µg/ml
- raised against amino acids 1-246 representing full length 14-3-3 β of human origin
- Anti-pan 14-3-3 Antibody (B-11) is recommended for detection of pan 14-3-3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-pan 14-3-3 Antibody (B-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of pan 14-3-3 (B-11): sc-133232.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for pan 14-3-3 Antibody (B-11). This work is in progress.
pan 14-3-3 Antibody (B-11) is an IgG1 κ mouse monoclonal pan 14-3-3 antibody (also designated pan 14-3-3 antibody or 14-3-3 antibody) that detects pan 14-3-3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. pan 14-3-3 Antibody (B-11) is available as the non-conjugated anti-pan 14-3-3 antibody form, as well as multiple conjugated forms of anti-pan 14-3-3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and Σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan 14-3-3 Antibody (B-11) | sc-133232 | 200 µg/ml | $310.00 | |||
pan 14-3-3 Antibody (B-11) AC | sc-133232 AC | 500 µg/ml, 25% agarose | $408.00 | |||
pan 14-3-3 Antibody (B-11) HRP | sc-133232 HRP | 200 µg/ml | $310.00 | |||
pan 14-3-3 Antibody (B-11) FITC | sc-133232 FITC | 200 µg/ml | $324.00 | |||
pan 14-3-3 Antibody (B-11) PE | sc-133232 PE | 200 µg/ml | $337.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 488 | sc-133232 AF488 | 200 µg/ml | $350.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 546 | sc-133232 AF546 | 200 µg/ml | $350.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 594 | sc-133232 AF594 | 200 µg/ml | $350.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 647 | sc-133232 AF647 | 200 µg/ml | $350.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 680 | sc-133232 AF680 | 200 µg/ml | $350.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 790 | sc-133232 AF790 | 200 µg/ml | $350.00 |