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CLN2 Antibody (D-11): sc-365838. Western blot analysis of CLN2 expression in CCRF-CEM (A), Hep G2 (B) and A-431 (C) whole cell lysates.
CLN2 Antibody (D-11): sc-365838
- CLN2 Antibody (D-11) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 264-563 mapping at the C-terminus of CLN2 of human origin
- recommended for detection of CLN2 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CLN2 Antibody (D-11) for WB applications. These reagents are now offered in bundles with CLN2 Antibody (D-11) (see ordering information below).
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Description
Gene Info
Protein Sequences
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Research Information
CLN2, also known as Tripeptidyl peptidase I (TTP-I), a member of the family of serine-carboxyl proteinases (S53), plays a crucial role in lysosomal protein degradation, and a deficiency in this enzyme leads to fatal neurodegenerative disease. CLN2 is a lysosomal aminopeptidase that sequentially removes tripeptides from small polypeptides and also shows a minor endoprotease activity. In lysosomes, CLN2 proenzyme is converted into a mature enzyme with the assistance of another protease and is able to autoactivate in acidic pH in vitro via an unimolecular mechanism.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CLN2 Antibody (D-11) | sc-365838 | 200 µg/ml | $310.00 | |||
CLN2 Antibody (D-11): m-IgG Fc BP-HRP Bundle | sc-540374 | 200 µg Ab; 10 µg BP | $348.00 | |||
CLN2 Antibody (D-11): m-IgG1 BP-HRP Bundle | sc-542079 | 200 µg Ab; 20 µg BP | $348.00 |