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DOCK 180 Antibody (E-2): sc-514080
- DOCK 180 Antibody (E-2) is a mouse monoclonal IgG1 κ DOCK 180 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 3-24 at the N-terminus of DOCK 180 of human origin
- DOCK 180 Antibody (E-2) is recommended for detection of DOCK 180 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-DOCK 180 Antibody (E-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of DOCK 180 (E-2): sc-514080.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DOCK 180 Antibody (E-2) for WB applications. These reagents are now offered in bundles with DOCK 180 Antibody (E-2) (see ordering information below).
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SEE ALSO...
DOCK 180 Antibody (E-2) is an IgG1 κ mouse monoclonal DOCK 180 antibody (also designated Dedicator Of Cytokinesis 1 antibody, DOCK180 antibody, Dedicator Of Cytokinesis Protein 1 antibody, 180 KDa Protein Downstream Of CRK antibody, DOwnstream Of CrK antibody, Ced5 antibody, or Dedicator Of Cyto-Kinesis 1 antibody) that detects the DOCK 180 protein of mouse, rat and human origin by WB, IP, IF and ELISA. DOCK 180 Antibody (E-2) is available as both the non-conjugated anti-DOCK 180 antibody form, as well as multiple conjugated forms of anti-DOCK 180 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The v-Crk oncogene product shares homologous amino acid sequences, designated Src homology region 2 (SH2) and SH3, with many molecules involved in signal transduction. The v-Crk cellular homolog, c-Crk, is a member of a newly emerging class of genes including Nck and GRB2/ASH which encode proteins that consist primarily of SH2 and SH3 domains. Two distinct human c-Crk cDNAs, designated Crk I and Crk II, have been identified and shown to represent alternative splice products of c-Crk. The major translational product of c-Crk I has been identified as a variably expressed protein, while c-Crk II encodes a widely expressed protein and a more variably expressed protein. The major c-Crk transforming activity appears associated with c-Crk I p28 expression. DOCK 180, a protein downstream of Crk, has been identified as a major Crk-associated protein. When DOCK 180 is recruited to the plasma membrane from a cytoplasmic reservoir, presumably by Crk, changes in cellular morphology and spindle formation occur, suggesting DOCK 180 to be a Crk effector molecule.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DOCK 180 Antibody (E-2) | sc-514080 | 200 µg/ml | $310.00 | |||
DOCK 180 Antibody (E-2): m-IgG Fc BP-HRP Bundle | sc-531023 | 200 µg Ab; 10 µg BP | $348.00 | |||
DOCK 180 Antibody (E-2): m-IgGκ BP-HRP Bundle | sc-524598 | 200 µg Ab, 40 µg BP | $348.00 | |||
DOCK 180 Antibody (E-2): m-IgG1 BP-HRP Bundle | sc-544362 | 200 µg Ab; 20 µg BP | $348.00 | |||
DOCK 180 Antibody (E-2) AC | sc-514080 AC | 500 µg/ml, 25% agarose | $408.00 | |||
DOCK 180 Antibody (E-2) HRP | sc-514080 HRP | 200 µg/ml | $310.00 | |||
DOCK 180 Antibody (E-2) FITC | sc-514080 FITC | 200 µg/ml | $324.00 | |||
DOCK 180 Antibody (E-2) PE | sc-514080 PE | 200 µg/ml | $337.00 | |||
DOCK 180 Antibody (E-2) Alexa Fluor® 488 | sc-514080 AF488 | 200 µg/ml | $350.00 | |||
DOCK 180 Antibody (E-2) Alexa Fluor® 546 | sc-514080 AF546 | 200 µg/ml | $350.00 | |||
DOCK 180 Antibody (E-2) Alexa Fluor® 594 | sc-514080 AF594 | 200 µg/ml | $350.00 | |||
DOCK 180 Antibody (E-2) Alexa Fluor® 647 | sc-514080 AF647 | 200 µg/ml | $350.00 | |||
DOCK 180 Antibody (E-2) Alexa Fluor® 680 | sc-514080 AF680 | 200 µg/ml | $350.00 | |||
DOCK 180 Antibody (E-2) Alexa Fluor® 790 | sc-514080 AF790 | 200 µg/ml | $350.00 | |||
DOCK 180 (E-2) Neutralizing Peptide | sc-514080 P | 100 µg/0.5 ml | $67.00 |