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Cytosolic malate dehydrogenase (MDHC or cMDH) is an important NAD-dependent enzyme involved in glycometabolism that catalyzes the formation of oxaloacetate and NADH from L-malate and NAD. MDHC is highly expressed in brain, heart and skeletal muscle and plays a role in aerobic energy production for muscle contraction, transmission of neuronal signals, absorption/ resorption pathways, collagen-supporting functions, dead cell phagocytosis, as well as pathways involved in gas exchange and cell division. Furthermore, MDHC is a regulatory subunit of the nucleic acid-conducting channel (NACh). MDHC functions as a homodimer and is highly conserved in plants, animals and bacteria. The activity of MDHC is controlled by the sesquiterpenoid juvenile hormone (JH) and the steroid hormone ecdysone.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MDHC Antibody (28) | sc-101516 | 200 µg/ml | $310.00 | |||
MDHC Antibody (28): m-IgG Fc BP-HRP Bundle | sc-539772 | 200 µg Ab; 10 µg BP | $348.00 |