NG2 Antibody (9.2.27): sc-80003
- NG2 Antibody (9.2.27) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- raised against urea extracts from M21 melanoma cells of human origin
- NG2 Antibody (9.2.27) is recommended for detection of precursor and mature NG2 and human melanoma, glioma and proliferating brain endothelial cells of human origin by IP, IF and FCM
- Anti-NG2 Antibody (9.2.27) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of NG2 (9.2.27): sc-80003.
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NG2 Antibody (9.2.27) for WB and IHC(P) applications. These reagents are now offered in bundles with NG2 Antibody (9.2.27) (see ordering information below).
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NG2 Antibody (9.2.27) is an IgG2a κ mouse monoclonal NG2 antibody that detects precursor and mature NG2 and human melanoma, glioma and proliferating brain endothelial cells of human origin by IP, IF and FCM. NG2 Antibody (9.2.27) is available as the non-conjugated anti-NG2 antibody form, as well as multiple conjugated forms of anti-NG2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. NG2 (also known as melanoma-associated chondroitin sulfate proteoglycan 4, MCSP, MCSPG, MSK16 and MEL-CSPG) stabilizes cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. NG2 may facilitate primary melanoma progression by enhancing the activation of key signaling pathways important for tumor invasion and growth. Threonine 2256 phosphorylation of rat NG2 (Threonine 2252 phosphorylation of human NG2) leads to redistribution of NG2 on the surface of astrocytomas, polarization of the cell and a significant increase in cell motility. NG2 acts as a co-receptor for spreading and focal contact formation in association with α4 β1 integrin in malignant melanoma cells. NG2 is present on blood vessels throughout the rat embryo. Microvessels within the rat CNS express NG2 on endothelial cells, and outside the CNS, NG2 is present on smooth muscle cells. NG2 is a novel marker for epidermal stem cells that contributes to their patterned distribution by promoting stem cell clustering.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NG2 Antibody (9.2.27) | sc-80003 | 200 µg/ml | $310.00 | |||
NG2 Antibody (9.2.27): m-IgGκ BP-HRP Bundle | sc-521153 | 200 µg Ab, 40 µg BP | $348.00 | |||
NG2 Antibody (9.2.27): m-IgG2a BP-HRP Bundle | sc-546086 | 200 µg Ab; 10 µg BP | $348.00 | |||
NG2 Antibody (9.2.27) AC | sc-80003 AC | 500 µg/ml, 25% agarose | $408.00 | |||
NG2 Antibody (9.2.27) HRP | sc-80003 HRP | 200 µg/ml | $310.00 | |||
NG2 Antibody (9.2.27) FITC | sc-80003 FITC | 200 µg/ml | $324.00 | |||
NG2 Antibody (9.2.27) PE | sc-80003 PE | 200 µg/ml | $337.00 | |||
NG2 Antibody (9.2.27) Alexa Fluor® 488 | sc-80003 AF488 | 200 µg/ml | $350.00 | |||
NG2 Antibody (9.2.27) Alexa Fluor® 546 | sc-80003 AF546 | 200 µg/ml | $350.00 | |||
NG2 Antibody (9.2.27) Alexa Fluor® 594 | sc-80003 AF594 | 200 µg/ml | $350.00 | |||
NG2 Antibody (9.2.27) Alexa Fluor® 647 | sc-80003 AF647 | 200 µg/ml | $350.00 | |||
NG2 Antibody (9.2.27) Alexa Fluor® 680 | sc-80003 AF680 | 200 µg/ml | $350.00 | |||
NG2 Antibody (9.2.27) Alexa Fluor® 790 | sc-80003 AF790 | 200 µg/ml | $350.00 |