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PAPSS 1 Antibody (A-8): sc-376306
- PAPSS 1 Antibody (A-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 288-329 mapping within an internal region of PAPSS 1 of human origin
- recommended for detection of PAPSS 1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for PAPSS 1 Antibody (A-8) for WB applications. These reagents are now offered in bundles with PAPSS 1 Antibody (A-8) (see ordering information below).
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Bifunctional 3′-phosphoadenosine 5′-phosphosulfate synthetases (PAPS synthetase or PAPSS), also designated sulfurylase kinase (SK), are important for sulfate assimilation in the sulfur metabolism pathway. PAPSS proteins are bifunctional enzymes with APS kinase and ATP sulfurylase activity, which mediate two steps in the sulfate activation pathway. The PAPSS proteins belong to the APS kinase family and to the sulfate adenylyltransferase family of proteins. In mammals, PAPSS proteins are the sole source of sulfate. PAPSS 1, which is involved in biosynthesis of sulfated L-selectin ligands in endothelial cells, is regulated by chlorate inhibition. It is expressed primarily in pancreas, liver, testis, thymus, kidney, prostate, ovary and small intestine.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PAPSS 1 Antibody (A-8) | sc-376306 | 200 µg/ml | $310.00 | |||
PAPSS 1 Antibody (A-8): m-IgG Fc BP-HRP Bundle | sc-540542 | 200 µg Ab; 10 µg BP | $348.00 | |||
PAPSS 1 Antibody (A-8): m-IgG1 BP-HRP Bundle | sc-542193 | 200 µg Ab; 20 µg BP | $348.00 |