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SVCT1 Antibody (H-11): sc-376090
- SVCT1 Antibody (H-11) is a mouse monoclonal IgG1 κ SVCT1 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 521-598 mapping at the C-terminus of SVCT1 of human origin
- SVCT1 Antibody (H-11) is recommended for detection of SVCT1 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-SVCT1 Antibody (H-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of SVCT1 (H-11): sc-376090.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SVCT1 Antibody (H-11) for WB and IHC(P) applications. These reagents are now offered in bundles with SVCT1 Antibody (H-11) (see ordering information below).
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SVCT1 Antibody (H-11) is an IgG1 κ mouse monoclonal SVCT1 antibody (also designated SVCT1 antibody) that detects the SVCT1 protein of human origin by WB, IP, IF, IHC(P) and ELISA. SVCT1 Antibody (H-11) is available as both the non-conjugated anti-SVCT1 antibody form, as well as multiple conjugated forms of anti-SVCT1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The sodium-dependent vitamin C transporters SVCT1 and SCVT2 are membrane transporters for L-ascorbic acid (Vitamin C). Both SVCT proteins mediate high affinity Na+-dependent L-ascorbic acid transport and are necessary for the uptake of vitamin C in many tissues. SVCT1 is a 604 amino acid protein that is expressed mainly in epithelial tissues, including intestine, kidney, and liver. SVCT2 is a 592 amino acid protein that shares 65% homology to SVCT1 and has been detected in various metabolically active cells as well as in specialized tissues such as eye and brain. A non-functional splice variant of SVCT1 has been identified in normal human intestine.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
References:
- A family of mammalian Na+-dependent L-ascorbic acid transporters. | Tsukaguchi, H., et al. 1999. Nature. 399: 70-5. PMID: 10331392
- Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function. | Rajan, DP., et al. 1999. Biochem Biophys Res Commun. 262: 762-8. PMID: 10471399
- Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): primary structure, functional characteristics and evidence for a non-functional splice variant. | Wang, H., et al. 1999. Biochim Biophys Acta. 1461: 1-9. PMID: 10556483
- Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2. | Daruwala, R., et al. 1999. FEBS Lett. 460: 480-4. PMID: 10556521
- Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters. | Faaland, CA., et al. 1998. Biochim Biophys Acta. 1442: 353-60. PMID: 9804989
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SVCT1 Antibody (H-11) | sc-376090 | 200 µg/ml | $310.00 | |||
SVCT1 Antibody (H-11): m-IgG Fc BP-HRP Bundle | sc-529820 | 200 µg Ab; 10 µg BP | $348.00 | |||
SVCT1 Antibody (H-11): m-IgGκ BP-HRP Bundle | sc-522843 | 200 µg Ab, 40 µg BP | $348.00 | |||
SVCT1 Antibody (H-11): m-IgG1 BP-HRP Bundle | sc-543706 | 200 µg Ab; 20 µg BP | $348.00 | |||
SVCT1 Antibody (H-11) AC | sc-376090 AC | 500 µg/ml, 25% agarose | $408.00 | |||
SVCT1 Antibody (H-11) HRP | sc-376090 HRP | 200 µg/ml | $310.00 | |||
SVCT1 Antibody (H-11) FITC | sc-376090 FITC | 200 µg/ml | $324.00 | |||
SVCT1 Antibody (H-11) PE | sc-376090 PE | 200 µg/ml | $337.00 | |||
SVCT1 Antibody (H-11) Alexa Fluor® 488 | sc-376090 AF488 | 200 µg/ml | $350.00 | |||
SVCT1 Antibody (H-11) Alexa Fluor® 546 | sc-376090 AF546 | 200 µg/ml | $350.00 | |||
SVCT1 Antibody (H-11) Alexa Fluor® 594 | sc-376090 AF594 | 200 µg/ml | $350.00 | |||
SVCT1 Antibody (H-11) Alexa Fluor® 647 | sc-376090 AF647 | 200 µg/ml | $350.00 | |||
SVCT1 Antibody (H-11) Alexa Fluor® 680 | sc-376090 AF680 | 200 µg/ml | $350.00 | |||
SVCT1 Antibody (H-11) Alexa Fluor® 790 | sc-376090 AF790 | 200 µg/ml | $350.00 |