Click on image or enlarge button to enlarge
apoA-I Antibody (12C8): sc-80551
- apoA-I Antibody (12C8) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 100 µg/ml
- raised against full length native apoA-I of human origin
- recommended for detection of apoA-I of mouse, rat and human origin by WB, IP and ELISA; non cross-reactive with apolipoprotein B (apoB)
- See Apolipoprotein A I/APOA1 (B-10): sc-376818 for apoA-I antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
apoA-I Antibody (12C8) | sc-80551 | 100 µg/ml | $289.00 |