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Dynamin II Antibody (B-2): sc-166526
- Dynamin II Antibody (B-2) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 853-870 at the C-terminus of Dynamin II of human origin
- recommended for detection of Dynamin II of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, bovine, porcine and canine; may cross-react with Dynamin III
- See Dynamin II (G-4): sc-166669 for Dynamin II antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Dynamin II Antibody (B-2). This work is in progress.
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Members of the dynamin family, including Dynamin I and Dynamin II, are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity. The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dynamin II Antibody (B-2) | sc-166526 | 200 µg/ml | $310.00 | |||
Dynamin II (B-2) Neutralizing Peptide | sc-166526 P | 100 µg/0.5 ml | $67.00 |