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ABHD5 Antibody (C-8): sc-393949
- ABHD5 Antibody (C-8) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 10-29 near the N-terminus of ABHD5 of human origin
- recommended for detection of ABHD5 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ABHD5 Antibody (C-8) for WB applications. These reagents are now offered in bundles with ABHD5 Antibody (C-8) (see ordering information below).
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Alpha/beta-hydrolase domains are characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. ABHD5 (abhydrolase domain containing 5), also known as CGI-58, NCIE2 or CDS, is a 349 amino acid protein that contains an alpha/beta-hydrolase domain through which it conveys catalytic function. Localized to the surface of lipid droplets, ABHD5 is widely expressed and interacts with Perilipin on the surface of lipid droplets where it facilitates lipolysis, the breakdown of fat. Defects in the gene encoding ABHD5 are the cause of Chanarin-Dorfman syndrome (CDS), an autosomal recessive inborn error of lipid metabolism with impaired long-chain fatty acid oxidation. CDS symptoms include congenital generalized ichthyosis, vacuolated leukocytes, hepatomegaly, myopathy, cataracts, neurosensory hearing loss and developmental delay.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ABHD5 Antibody (C-8) | sc-393949 | 200 µg/ml | $310.00 | |||
ABHD5 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-538342 | 200 µg Ab; 10 µg BP | $348.00 | |||
ABHD5 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-535935 | 200 µg Ab; 40 µg BP | $348.00 | |||
ABHD5 Antibody (C-8): m-IgG2b BP-HRP Bundle | sc-549940 | 200 µg Ab; 10 µg BP | $348.00 | |||
ABHD5 (C-8) Neutralizing Peptide | sc-393949 P | 100 µg/0.5 ml | $67.00 |