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COQ7 Antibody (B-12): sc-514029
- COQ7 Antibody (B-12) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 152-175 within an internal region of COQ7 of human origin
- recommended for detection of COQ7 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for COQ7 Antibody (B-12). This work is in progress.
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SEE ALSO...
COQ7, a Timing protein CLK-1 homolog, is a 217 amino acid protein encoded by the mouse gene Coq7. It is believed that COQ7/CLK-1 is required for the biosynthesis of Coenzyme Q (COQ), an essential co-factor in mitochondrial respiration. In yeast, mutation of the COQ7 gene results in the absence of UQ biosynthesis and demonstrates a role for this gene in the step leading to the hydroxylation of 5-demethoxyubiquinone. COQ7 may also be responsible for maintenance of mitochondrial integrity and neurogenesis. COQ7 is highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney. After transcription, COQ7 is targeted to the mitochondria where it is processed to its mature form. The protein similarities and the conservation of function of the CLK-1/clk-1/COQ7 gene products suggest a potential link between the production of ubiquinone and aging.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COQ7 Antibody (B-12) | sc-514029 | 200 µg/ml | $310.00 | |||
COQ7 (B-12) Neutralizing Peptide | sc-514029 P | 100 µg/0.5 ml | $67.00 |