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CRMP-2 Antibody (E-9): sc-376739
- CRMP-2 Antibody (E-9) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 509-543 near the C-terminus of CRMP-2 of human origin
- recommended for detection of CRMP-2 of mouse, rat, human and avian origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CRMP-2 Antibody (E-9) for WB and IHC(P) applications. These reagents are now offered in bundles with CRMP-2 Antibody (E-9) (see ordering information below).
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Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-2 is involved in axonal growth and guidance. The human CRMP-2 gene maps to 8p21.2, a chromosomal region that has been previously shown to have a significant linkage to schizophrenia and to several deficit symptoms of schizophrenia.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CRMP-2 Antibody (E-9) | sc-376739 | 200 µg/ml | $310.00 | |||
CRMP-2 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-535511 | 200 µg Ab; 40 µg BP | $348.00 | |||
CRMP-2 Antibody (E-9): m-IgG2b BP-HRP Bundle | sc-549436 | 200 µg Ab; 10 µg BP | $348.00 | |||
CRMP-2 (E-9) Neutralizing Peptide | sc-376739 P | 100 µg/0.5 ml | $67.00 |