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NF-M Antibody (1A2): sc-20013
- NF-M Antibody (1A2) is a mouse monoclonal IgG1 κ, cited in 11 publications, provided at 200 µg/ml
- raised against neurofilament purified from human brain
- recommended for detection of NF-M of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NF-M Antibody (1A2) for WB applications. These reagents are now offered in bundles with NF-M Antibody (1A2) (see ordering information below).
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Neurofilament-M (NF-M), for neurofilament medium polypeptide, a member of the intermediate filament family, is a major component of neuronal cytoskeletons. Neurofilaments are dynamic structures; they contain phosphorylation sites for a large number of protein kinases, including protein kinase A, protein kinase C, cyclin-dependent kinase 5, extracellular signal regulated kinase, glycogen synthase kinase-3, and stress-activated protein kinase gamma. In addition to their role in the control of axon caliber, neurofilaments may affect other cytoskeletal elements, such as microtubules and actin filaments. Changes in neurofilament phosphorylation or metabolism are frequently observed in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Parkinson′s disease, and Alzheimer′s disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NF-M Antibody (1A2) | sc-20013 | 200 µg/ml | $310.00 | |||
NF-M Antibody (1A2): m-IgG Fc BP-HRP Bundle | sc-538908 | 200 µg Ab; 10 µg BP | $348.00 | |||
NF-M Antibody (1A2): m-IgG1 BP-HRP Bundle | sc-541141 | 200 µg Ab; 20 µg BP | $348.00 |