p-Bad Antibody (F-6): sc-271963
- p-Bad Antibody (F-6) is a mouse monoclonal IgG1 κ, cited in 10 publications, provided at 200 µg/ml
- Anti-p-Bad Antibody (F-6) is recommended for detection of Ser 136 phosphorylated Bad of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-p-Bad Antibody (F-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of p-Bad (F-6): sc-271963.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for p-Bad Antibody (F-6) for WB applications. This reagent is now offered in a bundle with p-Bad Antibody (F-6) (see ordering information below).
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SEE ALSO...
p-Bad Antibody (F-6) is an IgG1 κ mouse monoclonal p-Bad antibody that detects Ser 136 phosphorylated Bad of mouse, rat and human origin by WB, IP, IF and ELISA. p-Bad Antibody (F-6) is available as the non-conjugated anti-p-Bad antibody form, as well as multiple conjugated forms of anti-p-Bad antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Phosphorylation of BAD, a pro-apoptotic member of the Bcl-2 protein family, on either serine 112 or serine 136 is thought to be necessary and sufficient for growth factors to promote cell survival. Serine 155 is a major site of phosphorylation by protein kinase A (PKA) and serum-induced kinases. Serine 155 phosphorylation requires the prior phosphorylation of serine 136, which recruits 14-3-3 proteins that then function to increase the accessibility of serine 155 to survival-promoting kinases. Like serine 112 and serine 136, phosphorylation of serine 155 inhibits the pro-apoptotic function of BAD. Serine 155 phosphorylation disrupts the binding of BAD to prosurvival Bcl-2 proteins and thereby promotes cell survival.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Bad Antibody (F-6) | sc-271963 | 200 µg/ml | $310.00 | |||
p-Bad Antibody (F-6): m-IgG Fc BP-HRP Bundle | sc-525841 | 200 µg Ab; 10 µg BP | $348.00 | |||
p-Bad Antibody (F-6) AC | sc-271963 AC | 500 µg/ml, 25% agarose | $408.00 | |||
p-Bad Antibody (F-6) HRP | sc-271963 HRP | 200 µg/ml | $310.00 | |||
p-Bad Antibody (F-6) FITC | sc-271963 FITC | 200 µg/ml | $324.00 | |||
p-Bad Antibody (F-6) PE | sc-271963 PE | 200 µg/ml | $337.00 | |||
p-Bad Antibody (F-6) Alexa Fluor® 488 | sc-271963 AF488 | 200 µg/ml | $350.00 | |||
p-Bad Antibody (F-6) Alexa Fluor® 546 | sc-271963 AF546 | 200 µg/ml | $350.00 | |||
p-Bad Antibody (F-6) Alexa Fluor® 594 | sc-271963 AF594 | 200 µg/ml | $350.00 | |||
p-Bad Antibody (F-6) Alexa Fluor® 647 | sc-271963 AF647 | 200 µg/ml | $350.00 | |||
p-Bad Antibody (F-6) Alexa Fluor® 680 | sc-271963 AF680 | 200 µg/ml | $350.00 | |||
p-Bad Antibody (F-6) Alexa Fluor® 790 | sc-271963 AF790 | 200 µg/ml | $350.00 | |||
p-Bad (F-6) Neutralizing Peptide | sc-271963 P | 100 µg/0.5 ml | $67.00 |