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beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11): sc-58627

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Datasheets
  • beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • raised against lamb Na+/K+-ATPase β1 from kidney tissue of ovine origin
  • recommended for detection of Na+/K+-ATPase β1 of mouse, rat and human origin by WB, IP and IF; also reactive with additional species, including and ovine and canine; non cross-reactive with the β1 or β2 subunits in rat
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11) for WB applications. These reagents are now offered in bundles with beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11) (see ordering information below).

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    The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, α, β and γ, comprise the Na+/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations; the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+/K+-ATPase.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11)

    sc-58627
    200 µg/ml
    $310.00

    beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11): m-IgG Fc BP-HRP Bundle

    sc-537153
    200 µg Ab; 10 µg BP
    $348.00

    beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11): m-IgGκ BP-HRP Bundle

    sc-534348
    200 µg Ab; 40 µg BP
    $348.00

    beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11): m-IgG2a BP-HRP Bundle

    sc-547935
    200 µg Ab; 10 µg BP
    $348.00

    What is the recommended secondary reagent to be used with sc-58627: Na+/K+-ATPase β1 (M17-P5-F11) mouse monoclonal primary?

    Asked by: Germaine
    We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-04-12
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    Rated 1 out of 5 by from Did not work well for western blotDid not work well for western blot for murine samples
    Date published: 2019-11-18
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    beta 1 Sodium Potassium ATPase/ATP1B1 Antibody (M17-P5-F11) is rated 1.5 out of 5 by 2.
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