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B7-2 Antibody (BU63): sc-19617
- B7-2 Antibody (BU63) is a mouse monoclonal IgG1 κ, cited in 17 publications, provided at 200 µg/ml
- raised against ARH-77 (B-lymphoblastoid cell line) of human origin
- Anti-B7-2 Antibody (BU63) is recommended for detection of B7-2 of resting monocytes and dendritic cells, and activated T, B and natural killer cells of mouse, rat and human origin by WB, IP, IF and FCM
- Anti-B7-2 Antibody (BU63) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of B7-2 (BU63): sc-19617.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for B7-2 Antibody (BU63) for WB applications. These reagents are now offered in bundles with B7-2 Antibody (BU63) (see ordering information below).
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B7-2 Antibody (BU63) is an IgG1 κ mouse monoclonal B7-2 antibody that detects B7-2 of resting monocytes and dendritic cells, and activated T, B and natural killer cells of mouse, rat and human origin by WB, IP, IF and FCM. B7-2 Antibody (BU63) is available as the non-conjugated anti-B7-2 antibody form, as well as multiple conjugated forms of anti-B7-2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins B7-1 (CD80) and B7-2 (CD86) expressed on antigen presenting cells bind the homologous T cell receptors CD28 and CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28, and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counterreceptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
B7-2 Antibody (BU63) | sc-19617 | 200 µg/ml | $310.00 | |||
B7-2 Antibody (BU63): m-IgG Fc BP-HRP Bundle | sc-526582 | 200 µg Ab; 10 µg BP | $348.00 | |||
B7-2 Antibody (BU63): m-IgG1 BP-HRP Bundle | sc-531955 | 200 µg Ab; 20 µg BP | $348.00 | |||
B7-2 Antibody (BU63) AC | sc-19617 AC | 500 µg/ml, 25% agarose | $408.00 | |||
B7-2 Antibody (BU63) HRP | sc-19617 HRP | 200 µg/ml | $310.00 | |||
B7-2 Antibody (BU63) FITC | sc-19617 FITC | 200 µg/ml | $324.00 | |||
B7-2 Antibody (BU63) PE | sc-19617 PE | 200 µg/ml | $337.00 | |||
B7-2 Antibody (BU63) Alexa Fluor® 488 | sc-19617 AF488 | 200 µg/ml | $350.00 | |||
B7-2 Antibody (BU63) Alexa Fluor® 546 | sc-19617 AF546 | 200 µg/ml | $350.00 | |||
B7-2 Antibody (BU63) Alexa Fluor® 594 | sc-19617 AF594 | 200 µg/ml | $350.00 | |||
B7-2 Antibody (BU63) Alexa Fluor® 647 | sc-19617 AF647 | 200 µg/ml | $350.00 | |||
B7-2 Antibody (BU63) Alexa Fluor® 680 | sc-19617 AF680 | 200 µg/ml | $350.00 | |||
B7-2 Antibody (BU63) Alexa Fluor® 790 | sc-19617 AF790 | 200 µg/ml | $350.00 |