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Bax Antibody (6A7): sc-23959
- Bax Antibody (6A7) is a mouse monoclonal IgG1 κ, cited in 249 publications, provided at 200 µg/ml
- raised against the N-terminal residues 12-24 common to human, mouse,and rat Bax protein
- Anti-Bax Antibody (6A7) is recommended for detection of Bax of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-Bax Antibody (6A7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Bax (6A7): sc-23959.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Bax Antibody (6A7) for WB and IHC(P) applications. This reagent is now offered in a bundle with Bax Antibody (6A7) (see ordering information below).
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Bax Antibody (6A7) is an IgG1 κ mouse monoclonal Bax antibody that detects Bax of mouse, rat and human origin by WB, IP, IF and IHC(P). Bax Antibody (6A7) is available as the non-conjugated anti-Bax antibody form, as well as multiple conjugated forms of anti-Bax antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Bcl-2 gene was isolated at the chromosomal breakpoint of t-bearing follicular B cell lymphomas. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 is localized to outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes. A related protein, designated Bax (Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activity of Bcl-2.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bax Antibody (6A7) | sc-23959 | 200 µg/ml | $310.00 | |||
Bax Antibody (6A7): m-IgG Fc BP-HRP Bundle | sc-525510 | 200 µg Ab; 10 µg BP | $348.00 | |||
Bax Antibody (6A7) AC | sc-23959 AC | 500 µg/ml, 25% agarose | $408.00 | |||
Bax Antibody (6A7) HRP | sc-23959 HRP | 200 µg/ml | $310.00 | |||
Bax Antibody (6A7) FITC | sc-23959 FITC | 200 µg/ml | $324.00 | |||
Bax Antibody (6A7) PE | sc-23959 PE | 200 µg/ml | $337.00 | |||
Bax Antibody (6A7) Alexa Fluor® 488 | sc-23959 AF488 | 200 µg/ml | $350.00 | |||
Bax Antibody (6A7) Alexa Fluor® 546 | sc-23959 AF546 | 200 µg/ml | $350.00 | |||
Bax Antibody (6A7) Alexa Fluor® 594 | sc-23959 AF594 | 200 µg/ml | $350.00 | |||
Bax Antibody (6A7) Alexa Fluor® 647 | sc-23959 AF647 | 200 µg/ml | $350.00 | |||
Bax Antibody (6A7) Alexa Fluor® 680 | sc-23959 AF680 | 200 µg/ml | $350.00 | |||
Bax Antibody (6A7) Alexa Fluor® 790 | sc-23959 AF790 | 200 µg/ml | $350.00 |