Bax Antibody (4H32): sc-70407
- Bax Antibody (4H32) is a mouse monoclonal IgG1 κ, cited in 40 publications, provided at 200 µg/ml
- raised against the N-terminal residues 12-24 common to human, mouse,and rat Bax protein
- recommended for detection of Bax of mouse, rat and human origin by WB and IP
- See Bax (B-9): sc-7480 for Bax antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Bax Antibody (4H32) for WB applications. These reagents are now offered in bundles with Bax Antibody (4H32) (see ordering information below).
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SEE ALSO...
The Bcl-2 gene was isolated at the chromosomal breakpoint of t-bearing follicular B cell lymphomas. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 is localized to outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes. A related protein, designated Bax (Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activity of Bcl-2.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bax Antibody (4H32) | sc-70407 | 200 µg/ml | $310.00 | |||
Bax Antibody (4H32): m-IgG Fc BP-HRP Bundle | sc-539273 | 200 µg Ab; 10 µg BP | $348.00 | |||
Bax Antibody (4H32): m-IgG1 BP-HRP Bundle | sc-541371 | 200 µg Ab; 20 µg BP | $348.00 |