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Bax Antibody (6D150): sc-70408
- Bax Antibody (6D150) is a mouse monoclonal IgG1 κ, cited in 30 publications, provided at 200 µg/ml
- raised against the N-terminal residues 12-24 common to human, mouse,and rat Bax protein
- recommended for detection of Bax of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See Bax (B-9): sc-7480 for Bax antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Bax Antibody (6D150) for WB and IHC(P) applications. These reagents are now offered in bundles with Bax Antibody (6D150) (see ordering information below).
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SEE ALSO...
The Bcl-2 gene was isolated at the chromosomal breakpoint of t-bearing follicular B cell lymphomas. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 is localized to outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes. A related protein, designated Bax (Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activity of Bcl-2.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bax Antibody (6D150) | sc-70408 | 200 µg/ml | $310.00 | |||
Bax Antibody (6D150): m-IgG Fc BP-HRP Bundle | sc-539274 | 200 µg Ab; 10 µg BP | $348.00 | |||
Bax Antibody (6D150): m-IgG1 BP-HRP Bundle | sc-541372 | 200 µg Ab; 20 µg BP | $348.00 |