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CD22 Antibody (4KB128): sc-20053
- CD22 Antibody (4KB128) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against human neoplastic cells from a case of hairy cell leukemia
- recommended for detection of CD22 of human origin by IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD22 Antibody (4KB128). This work is in progress.
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SEE ALSO...
The B lymphocyte specific CD22 antigen, also designated B-lymphocyte cell adhesion molecule (BLCAM), sialic acid-binding Ig-like lectin 2 (Siglec-2) and Leu-14, is a type I integral membrane glycoprotein, structurally similar to other cell adhesion molecules (CAMs), which acts as a regulator of B cell signaling. CD22 is expressed as both a cytoplasmic and membrane protein during discrete stages of B cell lymphocyte differentiation. The cytoplasmic form of CD22, expressed early in B cell development, is a useful marker for acute lymphocytic leukemia. The membrane form of CD22 is expressed in mature B cells prior to their differentiation into plasma cells. Alternative splicing results in two different isoforms, CD22α and CD22β. The CD22β monomer is the principally occurring isoform but CD22 also appears as a heterodimer of CD22β and the shorter isoform, CD22α.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD22 Antibody (4KB128) | sc-20053 | 200 µg/ml | $310.00 | |||
CD22 Antibody (4KB128) FITC | sc-20053 FITC | 200 µg/ml | $324.00 | |||
CD22 Antibody (4KB128) PE | sc-20053 PE | 200 µg/ml | $337.00 |