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CD35 Antibody (E-11): sc-7308
- CD35 Antibody (E-11) is a mouse monoclonal IgG1 κ CD35 antibody, cited in 6 publications, provided at 200 µg/ml
- raised against intact human monocytes
- CD35 Antibody (E-11) is recommended for detection of CD35 of human origin by WB, IP, IF, IHC(P), FCM and ELISA
- Anti-CD35 Antibody (E-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of CD35 (E-11): sc-7308.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD35 Antibody (E-11) for WB and IHC(P) applications. These reagents are now offered in bundles with CD35 Antibody (E-11) (see ordering information below).
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CD35 Antibody (E-11) is an IgG1 κ mouse monoclonal CD35 antibody (also designated CR1 antibody, Complement C3b/C4b Receptor 1 (Knops Blood Group) antibody, Complement Receptor Type 1 antibody, C3b/C4b Receptor antibody, CD35 Antigen antibody, C3BR antibody, KN antibody, C3-Binding Protein antibody, or C4BR antibody) that detects the CD35 protein of human origin by WB, IP, IF, IHC(P), FCM and ELISA. CD35 Antibody (E-11) is available as both the non-conjugated anti-CD35 antibody form, as well as multiple conjugated forms of anti-CD35 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. CD35, also called complement receptor 1 (CR1), functions as the receptor for complement components C3b and C4b, and it mediates the phagocytosis by neutrophils and monocytes of particles coated with C3b or C4b. CD35 is expressed on granulocytes, monocytes, B cells, some NK cells and erythrocytes. CD35 is implicated in systemic lupus erythematosus (SLE), a chronic systemic autoimmune disease characterized by the production of a broad spectrum of autoantibodies against nuclear, cytoplasmic, and cell surface antigens and an overload of the immune complex. There is an increased proteolytic cleavage of leukocyte cell surface CD35 in SLE patients. Sequence analysis suggests that Crry may be the mouse genetic homolog of the CD35 antigen encoded by the human gene CR1.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD35 Antibody (E-11) | sc-7308 | 200 µg/ml | $310.00 | |||
CD35 Antibody (E-11): m-IgG Fc BP-HRP Bundle | sc-526496 | 200 µg Ab; 10 µg BP | $348.00 | |||
CD35 Antibody (E-11): m-IgG1 BP-HRP Bundle | sc-531869 | 200 µg Ab; 20 µg BP | $348.00 | |||
CD35 Antibody (E-11) AC | sc-7308 AC | 500 µg/ml, 25% agarose | $408.00 | |||
CD35 Antibody (E-11) HRP | sc-7308 HRP | 200 µg/ml | $310.00 | |||
CD35 Antibody (E-11) FITC | sc-7308 FITC | 200 µg/ml | $324.00 | |||
CD35 Antibody (E-11) PE | sc-7308 PE | 200 µg/ml | $337.00 | |||
CD35 Antibody (E-11) Alexa Fluor® 488 | sc-7308 AF488 | 200 µg/ml | $350.00 | |||
CD35 Antibody (E-11) Alexa Fluor® 546 | sc-7308 AF546 | 200 µg/ml | $350.00 | |||
CD35 Antibody (E-11) Alexa Fluor® 594 | sc-7308 AF594 | 200 µg/ml | $350.00 | |||
CD35 Antibody (E-11) Alexa Fluor® 647 | sc-7308 AF647 | 200 µg/ml | $350.00 | |||
CD35 Antibody (E-11) Alexa Fluor® 680 | sc-7308 AF680 | 200 µg/ml | $350.00 | |||
CD35 Antibody (E-11) Alexa Fluor® 790 | sc-7308 AF790 | 200 µg/ml | $350.00 |