CD38 Antibody (2Q1628): sc-70654
- CD38 Antibody (2Q1628) is a rat monoclonal IgG2a, cited in 1 publications, provided at 200 µg/ml
- raised against partially purified CD38 from mouse bone marrow pre-B cells
- recommended for detection of CD38 of mouse origin by IF and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD38 Antibody (2Q1628). This work is in progress.
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SEE ALSO...
CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lymphocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabolites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD38 Antibody (2Q1628) | sc-70654 | 200 µg/ml | $310.00 |