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Integrin αV/β3/CD51/CD61 Antibody (BV3): sc-52684
- Integrin αV/β3/CD51/CD61 Antibody (BV3) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- recommended for detection of Integrin αV/β3 present on endothelium cells of human origin by IP and FCM
- available conjugated to FITC for IF, IHC(P) and FCM
- See Integrin αV/ITGAV/CD51 (P2W7): sc-9969 for Integrin αV/β3/CD51/CD61 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Integrin αV/β3/CD51/CD61 Antibody (BV3). This work is in progress.
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SEE ALSO...
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Integrin αV/β3/CD51/CD61 Antibody (BV3) | sc-52684 | 100 µg/ml | $310.00 | |||
Integrin αV/β3/CD51/CD61 Antibody (BV3) FITC | sc-52684 FITC | 100 tests in 2 ml | $324.00 |