Click on image or enlarge button to enlarge
α-dystroglycan Antibody (2237E2D1): sc-65628
- α-dystroglycan Antibody (2237E2D1) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against brain tissue homogenate, with epitope mapping to the glycosylation site of α-dystroglycan of bovine origin
- recommended for detection of brain α-dystroglycan of bovine origin by WB and IP; non cross-reactive with brain α-dystroglycan of mouse, rat and rabbit origin; non cross reactive with skeletal muscle α-dystroglycan
- See α-dystroglycan (IIH6): sc-53987 for α-dystroglycan antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for α-dystroglycan Antibody (2237E2D1) for WB applications. This reagent is now offered in a bundle with α-dystroglycan Antibody (2237E2D1) (see ordering information below).
QUICK LINKS
Dystroglycan (DG) is a cell surface receptor for several extracellular matrix molecules including laminins, Agrin and Perlecan. Dystroglycan function is required for the formation of basement membranes in early development and the organization of Laminin on the cell surface. α-dystroglycan is a membrane- associated, extracellular glycoprotein that is anchored to the cell-membrane by binding to the transmembrane glycoprotein α-dystroglycan to form an α/β-dystroglycan-complex. Additionally, dystroglycan is part of a multimolecular complex, where it associates with dystrophin, at the sarcolemma, to form the dystrophin-associated protein complex, or with utrophin, at the neuromuscular junction, to form the utrophin-associated protein complex. Dystroglycan is also thought to participate in the clustering of nicotinic acetylcholine receptors at the neuromuscular junction.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-dystroglycan Antibody (2237E2D1) | sc-65628 | 200 µg/ml | $310.00 | |||
α-dystroglycan Antibody (2237E2D1): m-IgG Fc BP-HRP Bundle | sc-539186 | 200 µg Ab; 10 µg BP | $348.00 |