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β-dystroglycan Antibody (A-9): sc-165999
- β-dystroglycan Antibody (A-9) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 831-895 mapping at the C-terminus of dystroglycan precursor of human origin
- recommended for detection of β-dystroglycan of mouse, rat and human origin by WB, IP, IF and ELISA
- See β-dystroglycan (4F7): sc-33702 for β-dystroglycan antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for β-dystroglycan Antibody (A-9) for WB applications. These reagents are now offered in bundles with β-dystroglycan Antibody (A-9) (see ordering information below).
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Dystroglycan (DG) is a cell surface receptor for several extracellular matrix molecules including laminins, agrin and perlecan. Dystroglycan function is required for the formation of basement membranes in early development and the organization of laminin on the cell surface. α-dystroglycan is a membrane-associated, extracellular glycoprotein that is anchored to the cell-membrane by binding to the transmembrane glycoprotein β-dystroglycan to form an α/β-dystroglycan-complex. Additionally, dystroglycan is part of a multimolecular complex, where it associates with dystrophin, at the sarcolemma, to form the dystrophin- associated protein complex or with utrophin, at the neuromuscular junction, to form the utrophin-associated protein complex. Dystroglycan is also thought to participate in the clustering of nicotinic acetylcholine receptors at the neuromuscular junction.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-dystroglycan Antibody (A-9) | sc-165999 | 200 µg/ml | $310.00 | |||
β-dystroglycan Antibody (A-9): m-IgG Fc BP-HRP Bundle | sc-539984 | 200 µg Ab; 10 µg BP | $348.00 | |||
β-dystroglycan Antibody (A-9): m-IgG1 BP-HRP Bundle | sc-541830 | 200 µg Ab; 20 µg BP | $348.00 |