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emerin Antibody (8A1): sc-81552
- emerin Antibody (8A1) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against full length recombinant emerin of human origin
- recommended for detection of emerin of mouse, rat and human origin by WB, IP and IF
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for emerin Antibody (8A1) for WB applications. These reagents are now offered in bundles with emerin Antibody (8A1) (see ordering information below).
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SEE ALSO...
Emerin is believed to be a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreyfuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Research has demonstrated that the lack of emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherentes in the heart. This may account for conduction defects in patients with EDMD.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
emerin Antibody (8A1) | sc-81552 | 200 µg/ml | $310.00 | |||
emerin Antibody (8A1): m-IgG Fc BP-HRP Bundle | sc-539623 | 200 µg Ab; 10 µg BP | $348.00 | |||
emerin Antibody (8A1): m-IgG1 BP-HRP Bundle | sc-541608 | 200 µg Ab; 20 µg BP | $348.00 |