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Cdc6 Antibody (D-1): sc-13136
- Cdc6 Antibody (D-1) is a mouse monoclonal IgG1 κ, cited in 12 publications, provided at 200 µg/ml
- raised against amino acids 257-560 of Cdc6 of human origin
- Cdc6 Antibody (D-1) is recommended for detection of Cdc6 of human origin by WB, IP, IF and ELISA
- Anti-Cdc6 Antibody (D-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Cdc6 (D-1): sc-13136.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Cdc6 Antibody (D-1) for WB applications. These reagents are now offered in bundles with Cdc6 Antibody (D-1) (see ordering information below).
Cdc6 Antibody (D-1) is an IgG1 κ mouse monoclonal Cdc6 antibody that detects Cdc6 of human origin by WB, IP, IF and ELISA. Cdc6 Antibody (D-1) is available as the non-conjugated anti-Cdc6 antibody form, as well as multiple conjugated forms of anti-Cdc6 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division control (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein Tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory Tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdc6 Antibody (D-1) | sc-13136 | 200 µg/ml | $310.00 | |||
Cdc6 Antibody (D-1): m-IgG Fc BP-HRP Bundle | sc-526539 | 200 µg Ab; 10 µg BP | $348.00 | |||
Cdc6 Antibody (D-1): m-IgG1 BP-HRP Bundle | sc-531912 | 200 µg Ab; 20 µg BP | $348.00 | |||
Cdc6 Antibody (D-1) AC | sc-13136 AC | 500 µg/ml, 25% agarose | $408.00 | |||
Cdc6 Antibody (D-1) HRP | sc-13136 HRP | 200 µg/ml | $310.00 | |||
Cdc6 Antibody (D-1) FITC | sc-13136 FITC | 200 µg/ml | $324.00 | |||
Cdc6 Antibody (D-1) PE | sc-13136 PE | 200 µg/ml | $337.00 | |||
Cdc6 Antibody (D-1) Alexa Fluor® 488 | sc-13136 AF488 | 200 µg/ml | $350.00 | |||
Cdc6 Antibody (D-1) Alexa Fluor® 546 | sc-13136 AF546 | 200 µg/ml | $350.00 | |||
Cdc6 Antibody (D-1) Alexa Fluor® 594 | sc-13136 AF594 | 200 µg/ml | $350.00 | |||
Cdc6 Antibody (D-1) Alexa Fluor® 647 | sc-13136 AF647 | 200 µg/ml | $350.00 | |||
Cdc6 Antibody (D-1) Alexa Fluor® 680 | sc-13136 AF680 | 200 µg/ml | $350.00 | |||
Cdc6 Antibody (D-1) Alexa Fluor® 790 | sc-13136 AF790 | 200 µg/ml | $350.00 |