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Cdk6 Antibody (DCS-90): sc-56282
- Cdk6 Antibody (DCS-90) is a mouse monoclonal IgG1 κ, cited in 9 publications, provided at 200 µg/ml
- raised against full length Cdk6 of human origin
- recommended for detection of Cdk6 of mouse, rat and human origin by WB, IP, IF and ELISA; non cross-reactive with other Cdk types
- See Cdk6 (DCS-83): sc-53638 for Cdk6 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cdk6 Antibody (DCS-90). This work is in progress.
Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Several Cdk proteins have been identified, including Cdk2-Cdk8, PCTAIRE-1-PCTAIRE-3, PITALRE and PITSLRE. Cdk6 is known to associate with cyclins D1, D2 and D3 and to be involved with the G1/S transition of the cell cycle. Multiple inhibitors of Cdk6 have been identified, including p18 and p19. These inhibitors bind to both free and complexed Cdk6, and they inhibit the activity of the cyclin D-bound Cdk6.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdk6 Antibody (DCS-90) | sc-56282 | 200 µg/ml | $310.00 |