Recombinant Human ADORA3 lysate

Cat.No. : ADORA3-12HCL
Product Overview : Over-expression cells lysed in RIPA buffer and lysate supplied in SDS loading buffer
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Source : HEK 293 cells
Species : Human
Molecular Mass : 39538.39Da
Recommended Usage : WB
Storage Instruction : Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Gene Name : ADORA3 adenosine A3 receptor [ Homo sapiens ]
Official Symbol : ADORA3
Synonyms : ADORA3; adenosine A3 receptor; adenosine receptor A3; AD026; A3AR; bA552M11.5; RP11-552M11.7;
Gene ID : 140
mRNA Refseq : NM_000677
Protein Refseq : NP_000668
MIM : 600445
UniProt ID : P33765
Chromosome Location : 1p21-p13
Pathway : Adenosine P1 receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem;
Function : G-protein coupled adenosine receptor activity; receptor activity; signal transducer activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (3)

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Are there any drugs currently on the market that target ADORA3 proteins? 08/27/2020

There are currently no drugs available that specifically target ADORA3 proteins. However, there are drugs that target other adenosine receptors, such as caffeine (which blocks adenosine receptors), methylxanthines (which block both adenosine A1 and A2A receptors), and antiarrhythmic drugs (which target adenosine A1 receptors in the heart).

What are ADORA3 proteins? 11/12/2019

ADORA3 proteins, also known as adenosine A3 receptors, are a subtype of adenosine receptors that are found in various tissues throughout the body including the brain, heart, lungs, liver, and immune cells. These receptors are responsible for mediating the effects of adenosine, a signaling molecule that regulates various physiological processes including inflammation, immune function, and cardiovascular function.

What are some challenges associated with developing drugs that target ADORA3 proteins? 02/01/2016

One challenge is the potential for side effects, as these receptors are found in multiple tissues throughout the body and have diverse effects on various physiological processes. Therefore, drugs targeting ADORA3 proteins may have off-target effects on other tissues and systems. Additionally, ADORA3-targeting drugs may need to be developed with specific dosing strategies or combinations with other medications to be effective against certain diseases.

Customer Reviews (3)

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Reviews
06/01/2021

    Its excellent solubility and stability properties have given me confidence in its reliability.

    10/17/2018

      The purity and consistency of this protein have surpassed my expectations, making it an ideal choice for my research.

      06/18/2018

        the technical team has been extremely responsive and knowledgeable, offering valuable insights and solutions to any concerns I had.

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