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Recombinant Human ALS2CL cell lysate

Cat.No. : ALS2CL-67HCL
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Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : ALS2CL ALS2 C-terminal like [ Homo sapiens ]
Official Symbol : ALS2CL
Synonyms : ALS2CL; ALS2 C-terminal like; ALS2 C-terminal-like protein; DKFZp686I0110; FLJ36525; RN49018; MGC129698; DKFZp686P238;
Gene ID : 259173
mRNA Refseq : NM_001190707
Protein Refseq : NP_001177636
MIM : 612402
UniProt ID : Q60I27
Chromosome Location : 3p21.31
Function : GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; identical protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What are the functional domains or motifs present in ALS2CL, and how do they contribute to its molecular functions? 06/07/2022

ALS2CL contains conserved domains, such as coiled-coil domains, which are involved in protein-protein interactions and may contribute to its cellular roles.

Can ALS2CL enzymatic activities be characterized, and what are their potential substrates or targets? 03/07/2022

The enzymatic activities of ALS2CL are not well-characterized, and further studies are required to determine its potential substrates and targets.

Can therapeutic interventions targeting ALS2CL or its associated pathways offer potential strategies for treating neurodegenerative disorders or other related conditions? 01/23/2021

Targeting ALS2CL or its associated pathways could hold potential therapeutic strategies for neurodegenerative disorders, aiming to restore proper membrane trafficking, neuronal connectivity, or synaptic function.

How does ALS2CL contribute to neuronal function or neuronal development, and are there any specific pathways or processes affected by ALS2CL? 07/12/2020

ALS2CL is involved in neuronal processes, such as neurite outgrowth and synaptic development, potentially through interactions with cytoskeletal components and signaling molecules.

Are there any genetic variations or mutations in ALS2CL associated with neurodegenerative diseases or other pathological conditions? 06/13/2020

There is limited evidence linking genetic variations or mutations in ALS2CL to neurodegenerative diseases or pathological conditions.

Does ALS2CL interact with other proteins or form complexes involved in cellular processes or signaling pathways? 03/31/2020

ALS2CL may interact with proteins involved in vesicle trafficking, protein sorting, or ER-Golgi transport, forming complexes critical for its functions.

What is the tissue-specific expression pattern of ALS2CL, and are there any factors that regulate its expression levels? 03/16/2019

ALS2CL exhibits a tissue-specific expression pattern, with higher expression levels observed in certain brain regions and neural tissues.

Does ALS2CL play a role in cellular processes such as vesicle trafficking, membrane dynamics, or cytoskeletal organization? 02/27/2019

ALS2CL is implicated in membrane trafficking events, including vesicle formation and fusion processes, contributing to cellular membrane dynamics.

Can ALS2CL expression or activity be modulated by post-translational modifications, and how do they impact its cellular functions? 01/02/2019

Post-translational modifications, such as phosphorylation or acetylation, may regulate ALS2CL activity, stability, or its interactions with other proteins.

What are the subcellular localization and distribution patterns of ALS2CL within cells, and does it exhibit any specific organelle associations? 09/23/2018

ALS2CL localizes to both the cytoplasm and cellular membranes, including the endoplasmic reticulum (ER) and Golgi apparatus.

Customer Reviews (3)

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Reviews
11/09/2022

    Comprehensive technical support from the supplier.

    05/21/2020

      Compatible with high-throughput screening platforms.

      06/27/2018

        Cost-effective solution for protein analysis.

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