Recombinant Human KMT2B Complex, His-tagged
Cat.No. : | KMT2B-131H |
Product Overview : | Recombinant Human MLL4 (2490-2715), WDR5 (22-334), RbBP5 (1-538), Ash2L (2-534), DPY-30 (1-99) protein, fused with N-terminal His-tag on all subunits, was expressed in E.coli. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | 20 mM Tris-HCl, pH 7.5, 300 mM NaCl, 1 mM TCEP (tris(2-carboxyethyl)phosphine HCl), 10% (w/v) glycerol, 1 µM ZnCl2. |
Molecular Mass : | 211.0 kDa |
Storage : | Store at -80°C. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles. |
Gene Name : | KMT2B lysine (K)-specific methyltransferase 2B [ Homo sapiens ] |
Official Symbol : | KMT2B |
Synonyms : | HRX2; MLL2; MLL4; TRX2; WBP7; MLL1B; WBP-7; CXXC10; WW domain binding protein 7; histone-lysine N-methyltransferase MLL4; mixed lineage leukemia gene homolog 2; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4; myeloid/lymphoid or mixed-lineage leukemia protein 4; trithorax homologue 2 |
Gene ID : | 9757 |
mRNA Refseq : | NM_014727 |
Protein Refseq : | NP_055542 |
MIM : | 606834 |
UniProt ID : | Q9UMN6 |
Chromosome Location : | 19q13.1 |
Pathway : | Chromatin modifying enzymes, organism-specific biosystem; Lysine degradation, organism-specific biosystem; PKMTs methylate histone lysines, organism-specific biosystem |
Function : | histone methyltransferase activity (H3-K4 specific); protein binding; transcription factor activity, sequence-specific DNA binding |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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