This immunotoxin was achieved by conjugating/fusing the Anti-IL2RA scFv to Diphtheriatoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to Hodgkin's lymphoma cells. Once bind, the toxin enters cells by receptor-mediated endocytosis, then Before the N-terminal 193 amino acids corresponding to the catalytic domain of DT enzyme; -II binding and elongation factor into the eukaryotic cell; the cell can catalyze specific elongation factor EF2 amide His699 of diphtheria ADP2 ribosylation occurs; thereby preventing protein synthesis and causes cell death. It was designed for treatment of Hodgkin's lymphoma.
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• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B073(A) | Recombinant Anti-human IL2RA Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
IAB-B073(G) | Recombinant Anti-human IL2RA Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
IAB-B073(T) | Recombinant Anti-human IL2RA Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-004 | Anti-Human CD25 Recombinant Antibody (Basiliximab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
PABX-030 | Recombinant Human Anti-CD25 Antibody (SDZCHII621) | Neut, FuncS | IgG |
PABX-030-F (E) | Recombinant Mouse Anti-CD25 Antibody Fab Fragment (SDZCHII621) | Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-155 | Anti-Human CD25 Recombinant Antibody (Inolimomab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
TAB-641LC | Anti-human IL2RA Recombinant Antibody (Inolimomab) (TAB-641LC) | ELISA | |
TAB-641LC-S(P) | Anti-human IL2RA scFv Fragment (Inolimomab) | ELISA | |
TAB-641LC-F(E) | Anti-human IL2RA Fab Fragment (Inolimomab) | ELISA | |
PABX-029-S (P) | Recombinant Human Anti-CD25 Antibody scFv Fragment (Daclizumab) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L027R | anti-IL2RA immunotoxin RFT5 (scFv)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L028E | anti-IL2RA immunotoxin RFT5 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L028D | anti-IL2RA immunotoxin RFT5 (IgG)-DT | Cytotoxicity assay, Functional assay | |
AGTO-L028R | anti-IL2RA immunotoxin RFT5 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L078E | IL2-PE immunotoxin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-608 | Human Anti-IL2RA Recombinant Antibody (clone RTF5); Fab Fragment | WB, FuncS | Chimeric (mouse/human) Fab |
FAMAB-0197CQ-F(E) | Mouse Anti-IL2RA Recombinant Antibody (clone 2C8); Fab Fragment | ELISA, WB, FC | Mouse Fab |
FAMAB-0198CQ-F(E) | Human Anti-IL2RA Recombinant Antibody (clone 4C1); Fab Fragment | ELISA, WB, FC | Chimeric (mouse/human) Fab |
FAMAB-0199CQ-F(E) | Mouse Anti-IL2RA Recombinant Antibody (clone 4F8); Fab Fragment | ELISA, WB, FC | Mouse Fab |
HPAB-M0454-YC-F(E) | Mouse Anti-IL2RA Recombinant Antibody; Fab Fragment (HPAB-M0454-YC-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-646LC | Anti-human IL2RA Recombinant Antibody (48M54S) (TAB-646LC) | FuncS | Humanized antibody |
TAB-647LC | Anti-human IL2RA Recombinant Antibody (48M51L) (TAB-647LC) | FuncS | Humanized antibody |
TAB-648LC | Anti-human IL2RA Recombinant Antibody (48V54S) (TAB-648LC) | FuncS | Humanized antibody |
TAB-649LC | Anti-human IL2RA Recombinant Antibody (Dmab) (TAB-649LC) | FC | Humanized antibody |
TAB-650LC | Human Anti-IL2RA Recombinant Antibody (TAB-650LC) | Block | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-642LC-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (TAB-642LC-S(P)) | ELISA, FC | Human scFv |
TAB-643LC-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (TAB-643LC-S(P)) | ELISA, FC | Human scFv |
TAB-644LC-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (TAB-644LC-S(P)) | ELISA, FC | Human scFv |
TAB-645LC-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (TAB-645LC-S(P)) | ELISA, FC | Human scFv |
PABX-030-S (P) | Recombinant Mouse Anti-CD25 Antibody scFv Fragment (SDZCHII621) | Neut, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1350CQ | Mouse Anti-IL2RA Recombinant Antibody (clone 2R12) | Block, FC, ICC, IF, IHC, IP, WB | Mouse IgG1 |
NEUT-1356CQ | Rat Anti-Il2ra Recombinant Antibody (VMC199) | FC, IP, IHC, Block, Depletion | Rat IgG1, λ |
NEUT-1357CQ | Rat Anti-Il2ra Recombinant Antibody (clone 3C7) | FC, IP, Inhib | Rat IgG2b, κ |
NEUT-1358CQ | Rat Anti-Il2ra Recombinant Antibody (clone mAb0817) | Block, Depletion | Rat IgG1 |
NEUT-1359CQ | Rat Anti-Il2ra Recombinant Antibody (clone mAb0845) | Block, FC, IHC-Fr, IP | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1351CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL264) | ELISA, Neut, WB | Mouse IgG2a |
NEUT-1352CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL231) | Neut, FC | Mouse IgG2a |
NEUT-1353CQ | Mouse Anti-IL2RA Recombinant Antibody (clone YC130) | ELISA, IHC, WB, Neut | Mouse IgG2a, κ |
NEUT-1354CQ | Mouse Anti-IL2RA Recombinant Antibody (clone SB-647) | ELISA, Neut, WB | Mouse IgG2a, κ |
NEUT-1355CQ | Rat Anti-Il2ra Recombinant Antibody (clone PC61.5) | FC, FuncS, Neut | Rat IgG1, λ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1808 | Rabbit Anti-IL2RA Recombinant Antibody (clone DS1808AB) | IHC, ICC, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0060-FY | Human Anti-IL2RA Recombinant Antibody (HPAB-0060-FY) | ELISA, PD | Humanized IgG1, κ |
HPAB-0197-FY | Mouse Anti-IL2RA Recombinant Antibody (clone WuTac) | FC, DB, WB | Mouse IgG |
HPAB-0559-WJ | Human Anti-IL2RA Recombinant Antibody (HPAB-0559-WJ) | ELISA, Inhib, FuncS, FC | Human IgG |
HPAB-0560-WJ | Human Anti-IL2RA Recombinant Antibody (HPAB-0560-WJ) | ELISA, Inhib, FuncS, FC | Human IgG |
HPAB-0561-WJ | Human Anti-IL2RA Recombinant Antibody (HPAB-0561-WJ) | ELISA, Inhib, FuncS, FC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-004 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Basiliximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-023 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Daclizumab), ADCC Enhanced | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
AFC-TAB-155 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Inolimomab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0559-WJ-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0559-WJ-S(P)) | ELISA, FC | Human scFv |
HPAB-0560-WJ-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0560-WJ-S(P)) | ELISA, FC | Human scFv |
HPAB-0561-WJ-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0561-WJ-S(P)) | ELISA, FC | Human scFv |
HPAB-2113-FY-S(P) | Mouse Anti-IL2RA Recombinant Antibody (clone MAK179); scFv Fragment | Inhib | Mouse scFv |
HPAB-1536WJ-S(P) | Rat Anti-IL2RA Recombinant Antibody; scFv Fragment (clone YTH 906.9.21) | ELISA, WB | Rat scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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