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Active Native Human C5b,6 Complex Protein

Cat.No. : C5b6-1537H
Product Overview : Native Human C5b,6 Complex Protein was purified from normal human serum.
  • Specification
  • Gene Information
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Description : C5b,6 is a product of complement activation of C5 and an intermediate in the formation of the C5b-9 membrane attack complex (MAC) of complement.
Source : Normal human serum
Species : Human
Form : Frozen liquid
Bio-activity : >10,000 Units/mg for lysis of sheep erythrocytes.
Molecular Mass : 285,000 Da (3 chains). C5b,6 is composed of two disulfide linked chains from C5b (105,000 and 75,000) and one unlinked chain from C6 (105,000).
Purity : >90% by SDS-PAGE
Unit Definition : One unit of lytic activity is defined as the amount of C5b,6 complex required to yield 50% lysis of 1.5x10^7 sheep erythrocytes when incubated for 30 minutes at 37 centigrade in a total reaction volume of 75 µL GVBE (10 mM EDTA) containing 500 ng C7, 500 ng C8, and 1000 ng C9.
Storage : Store at -70 centigrade or below. Avoid freeze/thaw.
Storage buffer : 10 mM HEPES, 120 mM NaCl, pH 7.2
Official Symbol : C5b,6 Complex
Official Symbol : C5b,6 Complex

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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