Active Recombinant Human ACLY Protein, GST-tagged
Cat.No. : | ACLY-420H |
Product Overview : | Recombinant Human ACLY fused with GST tag at the N-terminus was produced in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 10% glycerol, and 3 mM DTT. |
Bio-activity : | >300pmole/min/ug |
Molecular Mass : | 147 kDa |
Purity : | >86% |
Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Storage : | At least 6 months at -80 centigrade. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein(BSA 0.1-0.5%). |
Gene Name : | ACLY ATP citrate lyase [ Homo sapiens ] |
Official Symbol : | ACLY |
Synonyms : | ACLY; ATP citrate lyase; ATP-citrate synthase; ACL; ATP citrate synthase; ATPCL; CLATP; citrate cleavage enzyme; ATP-citrate (pro-S-)-lyase; |
Gene ID : | 47 |
mRNA Refseq : | NM_001096 |
Protein Refseq : | NP_001087 |
MIM : | 108728 |
UniProt ID : | P53396 |
Products Types
◆ Recombinant Protein | ||
ACLY-1907H | Recombinant Human ACLY Protein (4-265 aa), His-SUMO-tagged | +Inquiry |
ACLY-0221H | Recombinant Human ACLY Protein (M1-M1101), His tagged | +Inquiry |
ACLY-916H | Recombinant Human ACLY Protein, MYC/DDK-tagged | +Inquiry |
ACLY-0220H | Recombinant Human ACLY Protein (M1-M1101), Tag Free | +Inquiry |
Acly-252M | Recombinant Mouse Acly Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
ACLY-509HCL | Recombinant Human ACLY cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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