Recombinant Human C9, GST-tagged
| Cat.No. : | C9-26247TH |
| Product Overview : | Recombinant Human C9 full-length ORF (22 a.a. - 559 a.a) fussed with GST tag at N-terminal was expressed in Wheat Germ. |
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| Description : | This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC).The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. |
| Source : | Wheat Germ |
| Species : | Human |
| Tag : | GST |
| Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : | 84.92 kDa |
| AA Sequence : | QYTTSYDPELTESSGSASHIDCRMS PWSEWSQCDPCLRQMFRSRSIEVFG QFNGKRCTDAVGDRRQCVPTEPCED AEDDCGNDFQCSTGRCIKMRLRCNG DNDCGDFSDEDDCESEPRPPCRDRV VEESELARTAGYGINILGMDPLSTP FDNEFYNGLCNRDRDGNTLTYYRRP WNVASLIYETKGEKNFRTEHYEEQI EAFKSIIQEKTSNFNAAISLKFTPT ETNKAEQCCEETASSISLHGKGSFR FSYSKNETYQLFLSYSSKKEKMFLH VKGEIHLGRFVMRNRDVVLTTTFVD DIKALPTTYEKGEYFAFLETYGTHY SSSGSLGGLYELIYVLDKASMKRKG VELKDIKRCLGYHLDVSLAFSEISV GAEFNKDDCVKRGEGRAVNITSENL IDDVVSLIRGGTRKYAFELKEKLLR GTVIDVTDFVNWASSINDAPVLISQ KLSPIYNLVPVKMKNAHLKKQNLER AIEDYINEFSVRKCHTCQNGGTVIL MDGKCLCACPFKFEGIACEISKQKI SEGLPALEFPNEK |
| Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes : | Best use within three months from the date of receipt of this protein. |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Gene Name : | C9 complement component 9 [ Homo sapiens ] |
| Official Symbol : | C9 |
| Synonyms : | C9D; ARMD15; complement component C9 |
| Gene ID : | 735 |
| mRNA Refseq : | NM_001737 |
| Protein Refseq : | NP_001728 |
| MIM : | 120940 |
| UniProt ID : | P02748 |
| Chromosome Location : | 5p14-p12 |
| Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Complement Activation, Classical Pathway, organism-specific biosystem |
Products Types
| ◆ Recombinant Protein | ||
| C9-1149M | Recombinant Mouse C9 Protein, His (Fc)-Avi-tagged | +Inquiry |
| C9-349R | Recombinant Rat C9 Protein, His-tagged | +Inquiry |
| C9-714R | Recombinant Rat C9 Protein, His (Fc)-Avi-tagged | +Inquiry |
| C9-1845R | Recombinant Rabbit C9 protein, His & T7-tagged | +Inquiry |
| C9-3035Z | Recombinant Zebrafish C9 | +Inquiry |
| ◆ Native Protein | ||
| C9-58H | Native Human Complement C9 | +Inquiry |
| ◆ Lysates | ||
| C9-7945HCL | Recombinant Human C9 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionC9 mediates inflammation and is key in defense against bacterial infections.
C9 is crucial in forming the MAC, which lyses pathogens and damaged cells in immune defense.
C9 interacts with other complement components to propagate the complement cascade and immune response.
Variations in C9 function or expression can disrupt immune regulation, affecting disease susceptibility and severity.
C9 deficiency increases vulnerability to recurrent bacterial infections due to weakened immune response.
C9 influences ischemic injury outcomes by mediating inflammatory and immune responses.
In autoimmune diseases, C9 can exacerbate symptoms by overactivating the complement system.
Customer Reviews (3)
Write a reviewAccurate protein structural analysis, indispensable for our investigations.
Exceptional protein expression optimization support, highly appreciated.
Reliable mass spectrometry analysis, pivotal for advancing proteomics research.
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