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Recombinant Human CDC20

Cat.No. : CDC20-27897TH
Product Overview : Recombinant fragment corresponding to amino acids 1-100 of Human Cdc20 with an N terminal proprietary tag; Predicted MWt 36.63 kDa.
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Description : CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle.It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.
Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MAQFAFESDLHSLLQLDAPIPNAPP ARWQRKAKEAAGPAPSPMRAANRSH SAGRTPGRTPGKSSSKVQTTPSKPG GDRYIPHRSAAQMEVASFLLSKENQ
Sequence Similarities : Belongs to the WD repeat CDC20/Fizzy family.Contains 7 WD repeats.
Gene Name : CDC20 cell division cycle 20 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : CDC20
Synonyms : CDC20; cell division cycle 20 homolog (S. cerevisiae); CDC20 (cell division cycle 20, S. cerevisiae, homolog) , CDC20 cell division cycle 20 homolog (S. cerevisiae); cell division cycle protein 20 homolog; CDC20A; p55CDC;
Gene ID : 991
mRNA Refseq : NM_001255
Protein Refseq : NP_001246
MIM : 603618
Uniprot ID : Q12834
Chromosome Location : 1p34.1
Pathway : APC/C complex, organism-specific biosystem; APC/C complex, conserved biosystem; APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem;
Function : enzyme binding; protein C-terminus binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the potential side effects of inhibiting CDC20? 08/16/2021

Inhibiting CDC20 could potentially affect normal cell division, leading to adverse effects on healthy cells.

Could CDC20 be a prognostic marker for cancer? 04/02/2021

Some studies suggest that CDC20 levels might correlate with the prognosis of certain cancers, indicating the potential for predicting disease outcomes.

Are there any ongoing clinical trials related to CDC20? 08/29/2018

Several trials are exploring CDC20 inhibitors and their efficacy in cancer treatment.

How is CDC20 being targeted for therapeutic interventions? 06/27/2017

Research is investigating the inhibition of CDC20 as a potential strategy for cancer treatment.

Are there any medications targeting CDC20 currently available? 05/17/2016

No medications specifically targeting CDC20 have been approved, but research is ongoing in drug development.

Customer Reviews (3)

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Reviews
05/23/2022

    Its robust performance has significantly accelerated my research progress and contributed to the advancement of my scientific understanding.

    11/13/2021

      This protein has become an invaluable asset in my research, offering great versatility in its applications.

      11/07/2017

        The CDC20 protein stands out for its excellent quality, exceptional technical support, and wide range of applications.

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