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Recombinant Human FABP3 protein, His-tagged

Cat.No. : FABP3-506H
Product Overview : Recombinant Human FABP3 (Met1-Ala133) protein was fused to His-tag at C-terminus and expressed in E.coli.
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Description : Fatty acid-binding protein 3 (FABP3) is also known as Heart-type fatty acid binding protein (H-FABP), Mammary-derived growth inhibitor (MDGI), Muscle fatty acid-binding protein (M-FABP), FABP11, which belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. H-FABP/FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABP3 may also contribute to AS160 phosphorylation by maintaining insulin-dependent Akt activation in the cells under a lipotoxic condition.
Source : E.coli
Species : Human
Tag : His
Predicted N Terminal : Met1
Form : Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 15.7 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
Protein length : Met1-Ala133
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : FABP3
Official Symbol : FABP3
Synonyms : FABP3; fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); FABP11, fatty acid binding protein 11 , MDGI; fatty acid-binding protein, heart; H FABP; O FABP; fatty acid binding protein 11; mammary-derived growth inhibitor; muscle fatty acid-binding protein; Fatty acid-binding protein 3, muscle; heart-type fatty acid-binding protein; MDGI; FABP11; H-FABP; M-FABP; O-FABP
Gene ID : 2170
mRNA Refseq : NM_004102
Protein Refseq : NP_004093
MIM : 134651
UniProt ID : P05413

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is FABP3 different from other cardiac biomarkers like troponin? 10/18/2022

While troponin is specific to cardiac muscle and indicative of myocardial damage, FABP3 reflects early-stage cardiac injury and is more sensitive in certain contexts.

Are FABP3 levels specific to heart-related issues? 05/17/2021

While FABP3 is primarily associated with cardiac issues, elevated levels can also be observed in conditions affecting skeletal muscle.

Is FABP3 exclusively a diagnostic marker or does it have prognostic value? 04/25/2020

FABP3 not only helps in diagnosis but also has prognostic value, providing insights into the potential outcomes and recovery of cardiovascular patients.

Can FABP3 be used for early detection of heart attacks? 01/06/2020

Yes, FABP3 is considered a sensitive marker for early detection of myocardial infarction (heart attack).

How does FABP3 contribute to risk assessment in cardiovascular patients? 01/31/2017

Monitoring FABP3 levels helps assess the severity of cardiac damage and aids in risk stratification for cardiovascular events.

Customer Reviews (3)

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Reviews
07/01/2020

    In WB experiments, the FABP3 Protein consistently delivers exceptional performance.

    04/03/2018

      This protein has consistently demonstrated outstanding results, making it an indispensable tool in my research endeavors.

      12/07/2017

        The FABP3 Protein's applicability in protein electron microscopy structure analysis is remarkable.

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