Active Recombinant Human FCER1A, His-tagged
| Cat.No. : | FCER1A-725H |
| Product Overview : | Recombinant Human FCER1A (Accession # NP_001992) Val26-Gln205, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived. |
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| Source : | Mammalian cells |
| Species : | Human |
| Tag : | His |
| Predicted N Terminal : | Val26 |
| Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
| Bio-activity : | Measured by its binding ability in a functional ELISA.When Recombinant Human Fc epsilon RI alpha is immobilized at 2 µg/mL (100 µL/well), the concentration of human IgE that produces 50% of the optimal binding response is found to be approximately 0.05 - 0.2 µg/mL. |
| Molecular Mass : | Recombinant Human FCER1A, His-tagged has a calculated MW of 21.9 kDa. In SDS-PAGE migrates as 45-58 kDa, reducing conditions. |
| Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
| Gene Name : | FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide [ Homo sapiens ] |
| Official Symbol : | FCER1A |
| Synonyms : | FCER1A; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; FCE1A; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypeptide; high affinity immunoglobulin epsilon receptor alpha-subunit; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; FcERI; |
| Gene ID : | 2205 |
| mRNA Refseq : | NM_002001 |
| Protein Refseq : | NP_001992 |
| MIM : | 147140 |
| UniProt ID : | P12319 |
| Chromosome Location : | 1q23 |
Products Types
| ◆ Recombinant Protein | ||
| FCER1A-245H | Recombinant Human FCER1A Protein, His-tagged | +Inquiry |
| Fcer1a-8688M | Recombinant Mouse Fcer1a protein(Met1-Gln204), hFc-tagged | +Inquiry |
| FCER1A-1961R | Recombinant Rat FCER1A Protein, His (Fc)-Avi-tagged | +Inquiry |
| FCER1A-338H | Recombinant Human FCER1A Protein(Val26-Gln205), His-tagged | +Inquiry |
| FCER1A-2099H | Recombinant Human FCER1A Protein (26-205 aa), His-tagged | +Inquiry |
| ◆ Lysates | ||
| FCER1A-1394HCL | Recombinant Human FCER1A cell lysate | +Inquiry |
| FCER1A-1389MCL | Recombinant Mouse FCER1A cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionModulation of FCER1A expression can be achieved through techniques such as gene knockout, gene silencing, or gene transduction. In addition, its expression levels can also be affected by altering environmental factors such as nutrition, inflammation, etc.
The expression level of FCER1A can be detected by gene expression profiling or immunohistochemistry.
FCER1A plays a key role in the immune system, recognizing and presenting antigens to T cell receptors, thereby initiating an adaptive immune response.
Studies have shown that FCER1A is associated with the risk of some autoimmune diseases, inflammatory diseases, and certain cancers.
Studying FCER1A can help to gain insight into the mechanisms of immune response and inflammatory response, which is of great significance for the development of new drugs and therapeutic strategies. In addition, it is also of great value for understanding the pathogenesis and prevention of diseases.
FCER1A has complex associations with other genes and proteins, such as its interaction with T cell receptors, inflammatory factors, etc.
Customer Reviews (3)
Write a reviewFCER1A can maintain its biological activity and structural integrity under specific experimental conditions.
FCER1A quality is stable and reliable, with no significant differences between batches.
FCER1A has high chemical and physical stability and is suitable for long-term storage and use.
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